Prague Med. Rep. 2012, 113, 33-43

Antidiabetic and Neuroprotective Effects of Trigonella Foenum-graecum Seed Powder in Diabetic Rat Brain

P. Kumar1, R. K. Kale1, P. McLean2, Najma Zaheer Baquer1

1School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
2Division of Biosciences, Faculty of Life Sciences, University College London Medical School, London, UK

Received May 27, 2011
Accepted January 16, 2012

Crossref Cited-by Linking

  • Zameer Saima, Najmi Abul Kalam, Vohora Divya, Akhtar Mohd: A review on therapeutic potentials of Trigonella foenum graecum (fenugreek) and its chemical constituents in neurological disorders: Complementary roles to its hypolipidemic, hypoglycemic, and antioxidant potential. Nutritional Neuroscience 2018, 21, 539. <>
  • Semuyaba Ibrahim, Safiriyu Abass Alao, Tiyo Emmanuel Ayikobua, Niurka Remón Figueredo: Memory Improvement Effect of Ethanol Garlic (A. sativum) Extract in Streptozotocin-Nicotinamide Induced Diabetic Wistar Rats Is Mediated through Increasing of Hippocampal Sodium-Potassium ATPase, Glutamine Synthetase, and Calcium ATPase Activities. Evidence-Based Complementary and Alternative Medicine 2017, 2017, 1. <>
  • Vasant More Sandeep, Kim In-Su, Choi Dong-Kug: Recent Update on the Role of Chinese Material Medica and Formulations in Diabetic Retinopathy. Molecules 2017, 22, 76. <>
  • Ouzir Mounir, El Bairi Khalid, Amzazi Saaïd: Toxicological properties of fenugreek (Trigonella foenum graecum). Food and Chemical Toxicology 2016, 96, 145. <>
  • Duraiswamy Anand, Shanmugasundaram Devanand, Sasikumar Changam Sheela, Cherian Sanjay M., Cherian Kotturathu Mammen: Development of an antidiabetic formulation (ADJ6) and its inhibitory activity against α-amylase and α-glucosidase. Journal of Traditional and Complementary Medicine 2016, 6, 204. <>
  • Rosa Andrea Pereira, Jacques Carlos Eduardo Dias, de Souza Laila Oliveira, Bitencourt Fernanda, Mazzola Priscila Nicolao, Coelho Juliana Gonzales, Mescka Caroline Paula, Dutra-Filho Carlos Severo: Neonatal hyperglycemia induces oxidative stress in the rat brain: the role of pentose phosphate pathway enzymes and NADPH oxidase. Mol Cell Biochem 2015, 403, 159. <>
  • Kumar Pardeep, Taha Asia, Kumar Nitin, Kumar Vinod, Baquer Najma Zaheer: Sodium Orthovanadate and Trigonella Foenum Graecum Prevents Neuronal Parameters Decline and Impaired Glucose Homeostasis in Alloxan Diabetic Rats. Prague Med. Rep. 2015, 116, 122. <>
  • Gupta Suresh Kumar, Kumar Binit, Nag Tapas Chandra, Srinivasan B. P., Srivastava Sushma, Gaur Shrikant, Saxena Rohit: Effects of Trigonella foenum-graecum (L.) on retinal oxidative stress, and proinflammatory and angiogenic molecular biomarkers in streptozotocin-induced diabetic rats. Mol Cell Biochem 2014, 388, 1. <>
  • Król-Kogus B., Głód D., Krauze-Baranowska M., Matławska I.: Application of one- and two-dimensional high-performance liquid chromatography methodologies for the analysis of C-glycosylflavones from fenugreek seeds. Journal of Chromatography A 2014, 1367, 48. <>
  • Giribabu Nelli, Srinivasarao Nelli, Swapna Rekha Somesula, Muniandy Sekaran, Salleh Naguib: Centella asiaticaAttenuates Diabetes Induced Hippocampal Changes in Experimental Diabetic Rats. Evidence-Based Complementary and Alternative Medicine 2014, 2014, 1. <>
  • Kumar Pardeep, Taha Asia, Kale R. K., McLean P., Baquer Najma Zaheer: Beneficial effects of Trigonella foenum graecum and sodium orthovanadate on metabolic parameters in experimental diabetes. Cell Biochem Funct 2012, 30, 464. <>
Crossref Cited-by Linking logo