Prague Med. Rep. 2022, 123, 35-42

https://doi.org/10.14712/23362936.2022.4

Effective Treatment of a Melanoma Patient with Hemophagocytic Lymphohistiocytosis after Nivolumab and Ipilimumab Combined Immunotherapy

Renata Pacholczak-Madej1,2, Aleksandra Grela-Wojewoda2, Joanna Lompart2, Beata Żuchowska-Vogelgesang2, Marek Ziobro2

1Department of Anatomy, Jagiellonian University Medical College, Cracow, Poland
2Department of Clinical Oncology, The Maria Sklodowska-Curie National Research Institute of Oncology, Cracow, Poland

Received August 23, 2021
Accepted January 31, 2022

Crossref Cited-by Linking

  • Walmsley Charlotte S., Schoepflin Zachary, De Brabandt Charlotte, Rangachari Deepa, Berwick Shana, Patell Rushad: Hemophagocytic lymphohistiocytosis associated with immune checkpoint inhibitor use: A review of the current knowledge and future directions. Blood Cells, Molecules, and Diseases 2025, 110, 102896. <https://doi.org/10.1016/j.bcmd.2024.102896>
  • Xu Zhiya, Li Huilan, Yu Xinyi, Luo Jia, Zhang Zanling: Clinical characterization of hemophagocytic lymphohistiocytosis caused by immune checkpoint inhibitors: a review of published cases. Hematology 2024, 29. <https://doi.org/10.1080/16078454.2024.2340144>
  • Zhai Chongya, Jin Xuanhong, You Liangkun, Yan Na, Dong Jie, Qiao Sai, Zhong Yuhong, Zheng Yu, Pan Hongming: Hemophagocytic lymphohistiocytosis following pembrolizumab and bevacizumab combination therapy for cervical cancer: a case report and systematic review. BMC Geriatr 2024, 24. <https://doi.org/10.1186/s12877-023-04625-3>
  • Dirven Iris, Vander Mijnsbrugge An-Sofie, Mignon Sacha, Tijtgat Jens, Kint Nicolas, Neyns Bart: Auto-immune hemolytic anemia and hemophagocytic lymphohistiocytosis as immune-related adverse event in patients with metastatic melanoma and concurrent chronic lymphocytic leukemia: a case series and literature review. Melanoma Research 2023, 33, 338. <https://doi.org/10.1097/CMR.0000000000000895>
  • Liu Lisa L, Skribek Marcus, Harmenberg Ulrika, Gerling Marco: Systemic inflammatory syndromes as life-threatening side effects of immune checkpoint inhibitors: case report and systematic review of the literature. J Immunother Cancer 2023, 11, e005841. <https://doi.org/10.1136/jitc-2022-005841>
  • Ipilimumab/nivolumab/prednisone. Reactions Weekly 2022, 1913, 266. <https://doi.org/10.1007/s40278-022-18416-6>
  • Pacholczak-Madej Renata, Grela-Wojewoda Aleksandra, Puskulluoglu Miros\u0142awa, Lompart Joanna, Las-Jankowska Manuela, Krawczak Katarzyna, Wrona Ewa, Zar\u0119ba Lech, \u017bubrowska Justyna, Walocha Jerzy, Bazan-Socha Stanis\u0142awa, Ziobro Marek: Early Effects of Nivolumab and Ipilimumab Combined Immunotherapy in the Treatment of Metastatic Melanoma in Poland: A Multicenter Experience. Biomedicines 2022, 10, 2528. <https://doi.org/10.3390/biomedicines10102528>
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