Prague Med. Rep. 2023, 124, 449-455

https://doi.org/10.14712/23362936.2023.35

Paratesticular Dedifferentiated Liposarcoma with Rhabdomyoblastic Differentiation: A Case Report and Review of the Literature

Ahmet Keles1, Ozgur Arikan1, Ferhat Keser2, Ayse Nur Toksoz Yildirim3, Asif Yildirim1

1Department of Urology, Istanbul Medeniyet University, Istanbul, Turkey
2Department of Urology, Hakkari Yuksekova State Hospital, Hakkari, Turkey
3Department of Pathology, Istanbul Medeniyet University, Istanbul, Turkey

Received January 9, 2023
Accepted November 15, 2023

Liposarcomas of the paratesticular tissue is a rare pathological entity. The symptoms are similar to inguinal hernias or hydroceles. We present the case of an 84-year-old man with a rare paratesticular liposarcoma that manifested as painless right hemiscrotal swelling. Testicular tumour markers were negative. Imaging revealed a heterogeneous mass with a fat component. He underwent a radical orchiectomy on the left side to remove the associated mass. This revealed dedifferentiated liposarcoma (DDLS) with rhabdomyoblastic differentiation and MDM2 amplification. The surgical margins were negative, and the patient had a metastatic workup that included magnetic resonance imaging (MRI) of the abdomen and pelvis. Because of the disease’s rarity, there is no clear agreement on radiotherapy and chemotherapy roles.

References

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