Prague Med. Rep. 2025, 126, 55-62

https://doi.org/10.14712/23362936.2025.10

A Comprehensive Guide to Typhoidal Anemia

Jayanta Deb1,2ID, Suddha Sattwa Bandyopadhyay3ID, Sanjit Debnath4ID, Saurabh Gupta1ID

1Department of Biotechnology, GLA University, Mathura, Uttar Pradesh, India
2Department of Microbiology, AGMC and GBP Hospital, Kunjaban, Agartala, Tripura, India
3Department of Pathology, Gomati District Hospital, Tepania, Gomati, Tripura, India
4Department of Botany, Rabindranath Thakur Mahavidyalaya, Bishalgarh, Sipahijala District, Tripura, India

Received August 29, 2024
Accepted May 12, 2025

References

1. Anabire, N. G., Aryee, P. A., Helegbe, G. K. (2018) Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana. BMC Res. Notes 11(1), 1–6. <https://doi.org/10.1186/s13104-018-3456-9>
2. Barrett-Connor, E. (1972) Anemia and infection. Am. J. Med. 52(2), 242–253. <https://doi.org/10.1016/0002-9343(72)90073-3>
3. Brent, A. J., Oundo, J. O., Mwangi, I., Ochola, L., Lowe, B., Berkley, J. A. (2006) Salmonella bacteremia in Kenyan children. Pediatr. Infect. Dis. J. 25(3), 230–236. <https://doi.org/10.1097/01.inf.0000202066.02212.ff>
4. Brown, D. E., McCoy, M. W., Pilonieta, M. C., Nix, R. N., Detweiler, C. S. (2010) Chronic murine typhoid fever is a natural model of secondary hemophagocytic lymphohistiocytosis. PLoS One 5(2), e9441. <https://doi.org/10.1371/journal.pone.0009441>
5. Brown, D. E., Nick, H. J., McCoy, M. W., Moreland, S. M., Stepanek, A. M., Benik, R., O’Connell, K. E., Pilonieta, M. C., Nagy, T. A., Detweiler, C. S. (2015) Increased ferroportin-1 expression and rapid splenic iron loss occur with anemia caused by Salmonella enterica serovar Typhimurium infection in mice. Infect. Immun. 83(6), 2290–2299. <https://doi.org/10.1128/IAI.02863-14>
6. Butler, T., Islam, A., Kabir, I., Jones, P. K. (1991) Patterns of morbidity and mortality in typhoid fever dependent on age and gender: Review of 552 hospitalized patients with diarrhea. Rev. Infect. Dis. 13(1), 85–90. <https://doi.org/10.1093/clinids/13.1.85>
7. Chow, C. B., Leung, N. K. (1986) Anemia with typhoid fever. Pediatr. Infect. Dis. J. 5(4), 495. <https://doi.org/10.1097/00006454-198607000-00034>
8. Fukushima, S., Hagiya, H., Honda, H., Ishida, T., Hasegawa, K., Otsuka, F. (2023) A case of typhoid fever presenting with non-G6PD associated hemolytic anaemia. J. Travel Med. 30(6), taad092. <https://doi.org/10.1093/jtm/taad092>
9. Giannotta, J. A., Fattizzo, B., Cavallaro, F., Barcellini, W. (2021) Infectious complications in autoimmune hemolytic anemia. J. Clin. Med. 10(1), 164. <https://doi.org/10.3390/jcm10010164>
10. Hand, W. L., King, N. L. (1978) Serum opsonization of Salmonella in sickle cell anemia. Am. J. Med. 64(3), 388–395. <https://doi.org/10.1016/0002-9343(78)90217-6>
11. Hook, E. W., Campbell, C. G., Weens, H., Cooper, G. R. (1957) Salmonella osteomyelitis in patients with sickle-cell anemia. N. Engl. J. Med. 257(9), 403–407. <https://doi.org/10.1056/NEJM195708292570904>
12. James, J., Dutta, T. K., Jayanthi, S. (1997) Correlation of clinical and hematologic profiles with bone marrow responses in typhoid fever. Am. J. Trop. Med. Hyg. 57(3), 313–316. <https://doi.org/10.4269/ajtmh.1997.57.313>
13. Kaye, D., Hook, E. W. (1964) Influence of autoimmune hemolytic anemia on susceptibility to Salmonella infection. Proc. Soc. Exp. Biol. Med. 117(1), 20–23. <https://doi.org/10.3181/00379727-117-29486>
14. Kuo, C. C., Ku, S. C., Wang, J. T., Tsai, C. W., Wu, V. C., Chou, W. C. (2010) Psoas abscess caused by non-typhoid Salmonella in a patient with severe aplastic anemia. Yonsei Med. J. 51(3), 472–474. <https://doi.org/10.3349/ymj.2010.51.3.472>
15. Landesman, S. H., Rao, S. P., Ahonkhai, V. I. (1982) Infections in children with sickle cell anemia. Special reference to pneumococcal and Salmonella infections. J. Pediatr. Hematol. Oncol. 4(4), 407–416. <https://doi.org/10.1097/00043426-198224000-00008>
16. Loomis, W. P., Delaney, M. A., Johnson, M. L., Cookson, B. T. (2020) Failure of CD4 T cell-deficient hosts to control chronic nontyphoidal Salmonella infection leads to exacerbated inflammation, chronic anemia, and altered myelopoiesis. Infect. Immun. 89(1), e00417-20. <https://doi.org/10.1128/IAI.00417-20>
17. Mohamed, G., Aboelhassan, S., Zaki, M. E., Wahba, Y. (2020) Iron deficiency anemia and serum hepcidin level in children with typhoid fever: A case-control study. J. Pediatr. Infect. Dis. 15, 288–292.
18. Ndako, J. A., Dojumo, V. T., Akinwumi, J. A., Fajobi, V. O., Owolabi, A. O., Olatinsu, O. (2020) Changes in some haematological parameters in typhoid fever patients attending Landmark University Medical Center, Omuaran – Nigeria. Heliyon 6(5), e04002. <https://doi.org/10.1016/j.heliyon.2020.e04002>
19. Robbins, J. B., Pearson, H. A. (1965) Normal response of sickle cell anemia patients to immunization with Salmonella vaccines. J. Pediatr. 66(5), 877–882. <https://doi.org/10.1016/S0022-3476(65)80062-2>
20. Roux, C. M., Butler, B. P., Chau, J. Y., Paixao, T. A., Cheung, K. W., Santos, R. L., Luckhart, S., Tsolis, R. M. (2010) Both hemolytic anemia and malaria parasite-specific factors increase susceptibility to nontyphoidal Salmonella enterica serovar Typhimurium infection in mice. Infect. Immun. 78(4), 1520–1527. <https://doi.org/10.1128/IAI.00887-09>
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