Prague Med. Rep. 2025, 126, 162-166
https://doi.org/10.14712/23362936.2025.26
Factitiously Low Total Creatine Kinase Activity in Severe Rhabdomyolysis: A Case Series
Ariff Aizzat Abdul Razak1,2
, Wan Mohd Saifuhisam Wan Zain1,3, Wan Azman Wan Norlina1,3
, Wan Mohd Saifuhisam Wan Zain1,3, Wan Azman Wan Norlina1,3
1 Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
2 Pathology Unit, Faculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, Terengganu, Malaysia
3 Hospital Pakar Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Received February 4, 2025
Accepted August 27, 2025
References
1. , E., Bakan, N. (2021) Prevention of extra-analytical phase errors by non-analytical automation in clinical laboratory. Turk. J. Biochem. 46(3), 235–243.
<https://doi.org/10.1515/tjb-2020-0483>
2. , R., Sole-Enrech, G., Aparicio-Calvente, M. I. (2023) Definition of icteric interference index for six biochemical analytes. Biochem. Med. (Zagreb) 33(2), 020702.
<https://doi.org/10.11613/BM.2023.020702>
3. , C. J., Carter, A. C. (2016) Serum indices: Managing assay interference. Ann. Clin. Biochem. 53(5), 527–538.
<https://doi.org/10.1177/0004563216643557>
4. , A. K. (2020) Abnormal liver function tests associated with severe rhabdomyolysis. World J. Gastroenterol. 26(10), 1020–1028.
<https://doi.org/10.3748/wjg.v26.i10.1020>
5. Lopez, J., Burtis, C. A., Ashwood, E. R., Bruns, D. E. (2012) Tietz Textbook of Clinical Chemistry and Molecular Diagnosis, 5th Edition. Elsevier, St. Louis.
6. , K., Spanou, L. (2016) Acute kidney injury: Definition, pathophysiology and clinical phenotypes. Clin. Biochem. Rev. 37(2), 85–98.
7. , J. R., Mammen, A. L. (2015) Diagnostic evaluation of rhabdomyolysis. Muscle Nerve 51(6), 793–810.
<https://doi.org/10.1002/mus.24606>
8. , S. K., Dinakaran, A., Ray, L. (2016) Is dilution important: Factitious total creatine kinase in case of rhabdomyolysis? J. Clin. Diagn. Res. 10(10), BD01–BD02.
9. , V. (2022) Importance of observing the progress curve during enzyme assay in an automated clinical chemistry analyzer: A case study. EJIFCC 33(1), 56–62.
10. , P. A., Helmstetter, J. A., Kaye, A. M., Kaye, A. D. (2015) Rhabdomyolysis: Pathogenesis, diagnosis, and treatment. Ochsner J. 15(1), 58–69.
11. , C. J., Wiedermann, W., Joannidis, M. (2017) Causal relationship between hypoalbuminemia and acute kidney injury. World J. Nephrol. 6(4), 176–187.
<https://doi.org/10.5527/wjn.v6.i4.176>
12. , B., Zheng, R. (2019) Community-acquired pneumonia complicated by rhabdomyolysis: A clinical analysis of 11 cases. World J. Clin. Cases 7(24), 4218–4225.
<https://doi.org/10.12998/wjcc.v7.i24.4218>
