Prague Med. Rep. 2025, 126, 215-222
Radiological Analysis of Interhemispheric Fissure: A Comprehensive Study
, Renu Gupta2, Ashish K. Nayyar2, Surajit Ghatak2, Sarbesh Tiwari3, Jaskaran Singh Gosal4, Kumar Sambhav1
1 Department of Anatomy, All India Institute of Medical Sciences, Bilaspur, Himachal Pradesh, India
2 Department of Anatomy, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
3 Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
4 Department of Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
Received February 5, 2025
Accepted November 21, 2025
Interhemispheric fissure is the midline groove present between the cerebral hemispheres. It provides access to corpus callosum, lateral ventricles and third ventricle during interhemispheric approach in neurosurgery. The knowledge and established data about its morphometry are limited. 90 participants who underwent magnetic resonance imaging scans were studied. The data was divided into 4 age groups (25–45, 45–65, 65–85 and >85 years) as well as among males and females. The depth of interhemispheric fissure was measured from 6 predetermined reference points from the superomedial border of cerebral hemisphere to the floor of corpus callosum which is formed by corpus callosum. Mean along with standard deviation and confidence interval were calculated. Unpaired t-test and ANOVA was used to analyse the statistical difference between various age groups. The mean value of depth of interhemispheric fissure from frontal pole to genu is 35.08 ± 3.20 mm, at the level of coronal suture is 35.64 ± 4.27 mm, 1 cm anterior to coronal suture is 35.50 ± 3.27 mm, 1 cm posterior to coronal suture is 34.38 ± 4.95 mm. The depth from superomedial border at the level of parietooccipital sulcus is 43.72 ± 3.63 mm and at the level of calcarine sulcus is 54.13 ± 5.96 mm. This data is useful for neurosurgeons in order to perform interhemispheric approach.
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