Prague Med. Rep. 2026, 127, 137-139

https://doi.org/10.14712/23362936.2026.20

Plasma Cell Vulvitis (Zoon’s Vulvitis): A Rare Case Report with Emphasis on Diagnostic Challenge

Gyanendra Singh1ID, Urmila Sunda1, Vishal Tayde2ID, Ridhhi Parmar1

1All India Institute of Medical Sciences, Rajkot, Gujarat, India
2Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra, India

Received October 30, 2024
Accepted June 2, 2026

References

1. Botros, S. M., Dieterich, M., Sand, P. K., Goldberg, R. P. (2006) Successful treatment of Zoon vulvitis with high potency topical steroid. Int. Urogynecol. J. Pelvic Floor Dysfunct. 17, 178. <https://doi.org/10.1007/s00192-005-1289-2>
2. Brix, W. K., Nassau, S. R., Patterson, J. W., Cousar, J. B., Wick, M. R. (2010) Idiopathic lympho-plasma cellular mucositis-dermatitis. J. Cutan. Pathol. 37, 426. <https://doi.org/10.1111/j.1600-0560.2009.01371.x>
3. Damiani, L., de Quadros, M., Posser, V., Minotto, R., Boff, A. L. (2017) Zoon vulvitis. An. Bras. Dermatol. 92(5 Suppl. 1), 166–168. <https://doi.org/10.1590/abd1806-4841.20175622>
4. Doherty, M. G., Van Dinh, T., Payne, D., Tyring, S. K., Hannigan, E. V. (1993) Chronic plasma cell cervicitis simulating a cervical malignancy: A case report. Obstet. Gynecol. 82(4 Pt 2 Suppl.), 646–650.
5. Goldstein, A. T., Christopher, K., Burrows, L. J. (2005) Plasma cell vulvitis: A rare cause of intractable vulvar pruritus. Arch. Dermatol. 141(6), 789–790. <https://doi.org/10.1001/archderm.141.6.789>
6. Joshi, U. Y. (1999) Carcinoma of the penis preceded by Zoon’s balanitis. Int. J. STD AIDS 10, 823–825. <https://doi.org/10.1258/0956462991913484>
7. Morioka, S., Nakajima, S., Yaguchi, H., Naito, K., Iwahara, K., Ogawa, H. (1988) Vulvitis circumscripta plasmacellularis treated successfully with interferon alpha. J. Am. Acad. Dermatol. 19 (5 Pt 2), 947–950. <https://doi.org/10.1016/S0190-9622(88)70256-X>
8. Neri, I., Patrizi, A., Marzaduri, S., Marini, R., Negosanti, M. (1995) Vulvitis plasma cellularis: Two new cases. Genitourin. Med. 71, 311–313.
9. Virgili, A., Corazza, M., Minghetti, S., Borghi, A. (2015) Symptoms in plasma cell vulvitis: First observational cohort study on type, frequency and severity. Dermatology 230(2), 113–118. <https://doi.org/10.1159/000367786>
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ISSN 1214-6994 (Print) ISSN 2336-2936 (Online)

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