Prague Med. Rep. 2026, 127, 225-228
https://doi.org/10.14712/23362936.2026.30
Siliconomas and Sepsis from Illegal Silicone Injections
Manuela Montatore1
, Gianmichele Muscatella1, Federica Masino1, Alessio Sciacqua1, Marina Balbino1, Rossella Gifuni1, Giuseppe Guglielmi1,2,3
, Gianmichele Muscatella1, Federica Masino1, Alessio Sciacqua1, Marina Balbino1, Rossella Gifuni1, Giuseppe Guglielmi1,2,3
1Department of Clinical and Experimental Medicine, School of Medicine, University of Foggia, Foggia, Italy
2Radiology Unit, “Dimiccoli” Hospital, Barletta, Italy
3Radiology Unit, IRCCS “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo, Italy
Received November 26, 2024
Accepted September 8, 2026
References
1. , B. S., de Balassiano, L. K., de Bastos, J. T., da Rocha, C. R., Costa, M. B., de Freire Cassia, F., Bravo, L. (2016) Siliconoma: Report of two cases. Aesthetic Plast. Surg. 40(2), 288–292.
<https://doi.org/10.1007/s00266-016-0618-9>
2. , P. E. (2007) The history of injectable silicone fluids for soft-tissue augmentation. Plast. Reconstr. Surg. 120(7), 2034–2040.
<https://doi.org/10.1097/01.prs.0000267580.92163.33>
3. , Y. C., Su, M. Y., Ng, S. H., Lee, K. F., Chen, S. C., Lo, Y. F. (2002) Lumpy silicone-injected breasts: Enhanced MRI and microscopic correlation. Clin. Imaging 26(6), 397–404.
<https://doi.org/10.1016/S0899-7071(02)00453-9>
4. , L., Morrison, D., Kop, A., Taylor, D. (2014) Breast augmentation with an unknown substance. BMJ Case Rep. 2014, bcr2014204535.
<https://doi.org/10.1136/bcr-2014-204535>
5. , R., Eusebi, L., Masino, F., Testini, V., Guglielmi, G. (2023) A rare case of siliconomas resulting from free silicone injections in breast tissue. Acta Biomed. 94(S1), e2023023.
6. , R., Engineer, N. (2008) Surreptitious injection of mineral oil: A case report of sclerosing lipogranulomatosis. Ann. Plast. Surg. 61(5), 555–558.
<https://doi.org/10.1097/SAP.0b013e31816d8316>
7. , S. K., Chen, G. P., Sun, Z. S., Cheng, N. X. (2011) Our strategy in complication management of augmentation mammaplasty with polyacrylamide hydrogel injection in 235 patients. J. Plast. Reconstr. Aesthet. Surg. 64(6), 731–737.
<https://doi.org/10.1016/j.bjps.2010.10.004>
8. , R. S., Beer, K. (2006) Liquid injectable silicone: A review of its history, immunology, technical considerations, complications, and potential. Plast. Reconstr. Surg. 118(3 Suppl.), 77S–84S.
<https://doi.org/10.1097/01.prs.0000234919.25096.67>
9. , R., Karim, K., Parikh, N., Han, P., Daoko, J., Shamoon, F. E. (2008) Case report and literature review: Acute pneumonitis and alveolar hemorrhage after subcutaneous injection of liquid silicone. Ann. Clin. Lab. Sci. 38(4), 380–385.
10. , M. J., Vinnik, C., Zarem, H. (1996) Injectable silicone: Cause of facial nodules, cellulitis, ulceration, and migration. Aesthetic Plast. Surg. 20(3), 267–276.
<https://doi.org/10.1007/s002669900032>
11. , A. M., de Fátima Ribeiro Maia, M. (2006) Sonographic and mammographic findings of breast liquid silicone injection. J. Clin. Ultrasound 34(6), 273–277.
<https://doi.org/10.1002/jcu.20235>
12. , T., Gschnitzer, C., Wechselberger, G., Otto, A., Hussl, H., Piza-Katzer, H. (2000) Chronic recurrent, locally destructive siliconomas after breast augmentation by liquid silicone oil. Chirurg 71(11), 1370–1373. (in German)
<https://doi.org/10.1007/s001040051228>
13. , E. M., Hametti, J. M., Romanelli, P., Ricotti, C. (2008) Foreign body granuloma formation secondary to silicone injection. Dermatol. Online J. 14(7), 20.
<https://doi.org/10.5070/D37JX780XV>
14. , M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J. D., Coopersmith, C. M., Hotchkiss, R. S., Levy, M. M., Marshall, J. C., Martin, G. S., Opal, S. M., Rubenfeld, G. D., van der Poll, T., Vincent, J. L., Angus, D. C. (2016) The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 315(8), 801–810.
<https://doi.org/10.1001/jama.2016.0287>
15. , T. F. (1977) Late development of granuloma after liquid silicone injections. Plast. Reconstr. Surg. 60(2), 179–188.
<https://doi.org/10.1097/00006534-197708000-00004>
