Prague Med. Rep. 2013, 114, 35-38

Isolated Extrapontine Myelinolysis of Osmotic Demyelination Syndrome

Ömer Yılmaz1,*, H. H. Armağn2, A. Turan3, M. Duymuş4

1Department of Radiology, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey
2Department of Emergency, Isparta State Hospital, Isparta, Turkey
3Department of Radiology, Etlik Training and Research Hospital,  Ankara, Turkey
4Department of Radiology, Faculty of Medicine, Kafkas Kars University, Kars, Turkey

The osmotic demyelination syndrome (ODS) has been identified as a complication of the rapid correction of hyponatremia for decades (King and Rosner, 2010). However, in recent years, a variety of other medical conditions have been associated with the development of ODS, independent of changes in serum sodium which cause a rapid changes in osmolality of the interstitial (extracellular) compartment of the brain leading to dehydration of energy-depleted cells with subsequent axonal damage that occurs in characteristic areas (King and Rosner, 2010). Slow correction of the serum sodium concentration and additional administration of corticosteroids seems to be a major prevention step in ODS patients. In the current report we aimed to share a rare case which we observed in our clinic.


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