Prague Med. Rep. 2020, 121, 262-266

https://doi.org/10.14712/23362936.2020.23

A Severe Case of Anaplastic Large Cell Lymphoma in a Previously Healthy Woman: Diagnostic and Therapeutic Challenges

Petya Angelova1, Robert Brock1, Alexandra-Teodora Negoescu1, Lara-Marie Schmitt2, Julia Meißner2, Sascha Dietrich2, Carsten Müller-Tidow2, Jan Philipp Novotný2

1Heidelberg Medical Faculty, Heidelberg University, Heidelberg, Germany
2Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

Received May 9, 2020
Accepted November 2, 2020

Anaplastic large cell lymphomas are an aggressive subtype of peripheral T-cell lymphomas that can manifest with a variety of symptoms. Our case highlights the importance of prompt tissue sampling, especially if an associated hemophagocytic lymphohistiocytosis is detected and no clinical improvement is observed upon glucocorticoid treatment.

References

13 live references

Open full article