Prague Med. Rep. 2024, 125, 62-68

Recurrent Stroke as a Presenting Feature of Takayasu Arteritis in an Adolescent: A Case Report and Literature Review

Vasiliki Sgouropoulou1, Efthymia Vargiami1, Maria Kyriazi1, Sofia Kafterani1, Stella Stabouli1, Georgios Tsigaras1, Athanasia Anastasiou2, Maria Trachana1, Dimitrios Zafeiriou1

11st Department of Paediatrics, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
2Department of Radiology, Hippokration General Hospital, Thessaloniki, Greece

Received July 6, 2023
Accepted January 30, 2024

Takayasu arteritis is a large vessel vasculitis, characterized by granulomatous inflammation of arterial vessels, that typically affects the aorta, its main branches and pulmonary arteries. Disease diagnosis is a challenge and requires awareness of the condition, as clinical signs can be not specific. We report a case of an adolescent with recurrent stroke diagnosed with Takayasu arteritis. A diagnosis of Takayasu arteritis was established due to angiographic findings in the magnetic resonance angiography in conjunction with systolic blood pressure discrepancy, arterial hypertension and increased acute phase reactants. Takayasu arteritis is a rare cause of ischemic stroke in children. However, stroke may be the first manifestation of the disease. Clinical experience and multidisciplinary approach, including aggressive treatment, is essential for the favourable outcome of the disease and the reduction of the associated morbidity and mortality.


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